
Viral Decay Acceleration™: Disrupting Viral Stability
The Viral Decay Acceleration™ (VDA) technology is based on the concept of viral quasispecies, which refers to a virus population made up of many different genetic variants that are always changing. This diversity is caused by the virus’s replication error rate. There is a critical error threshold—if this error rate becomes too high, the viral population collapses, a process known as error catastrophe.
The diversity of the viral population is also influenced by its environment, such as the host’s immune system or drug treatments, which put pressure on the virus. The virus has a naturally high mutation rate, allowing it to quickly develop resistance to drugs when exposed to treatment.
Error Catastrophe to Eliminate Viruses
Viral Decay Acceleration™ works by introducing additional errors into the viral genome using compounds that cause incorrect base pairings during replication. This increases the mutation rate, pushing the virus beyond its threshold of viability. As a result, the viral population becomes unstable and eventually disappears. This approach is being used to treat viruses like HIV and HCV by speeding up their elimination.
