Publications By Koronis And Its Advisors:

1. Harris, K.S., Brabant, W., Styrchak, S., Gall, A., Diafuku, R. KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis. Antiviral research. 2005; 67: 1-9.

2. Murakami, E., Basavapathrumi, A., Bradley, W.D., Anderson, K.S. Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host DNA polymerases. Antiviral Research. 2005; 67:10-17.

3. Smith, R.A., Loeb, L.A., Preston, B.D. Lethal mutagenesis of HIV. Viral Research. 2005; 107:215-228.

4. Anderson, J.P., Daifuku, R., Loeb, L.A. Viral error catastrophe by mutagenic nucleosides. Annual Review of Microbiology. 2004; September:58.

5. Daifuku, R. Stealth Nucleosides: mode of action and potential use in the treatment of viral diseases. BioDrugs. 2003; 17(3):169-177.

6. Li, L., Faske, S.K., Daifuku, R. Broad spectrum antiviral activity of a novel mutagenic ribonucleoside analog. Program and Abstracts of the Forty-First Interscience Conference on Antimicrobials and Chemotherapy. 2001. Abstract F-1675, p.239.

7. Loeb, L.A., Mullins, J.I. Lethal mutagenesis of HIV by mutagenic ribonucleoside analogs. AIDS Research and Human Retroviruses. 2000; 16:1-3.

8. Loeb, L.A., Essigmann, J.M., Farhad, K., Zhang, J., Rose, K.D., Mullins, J.I. Lethal mutagenesis of HIV with mutagenic nucleoside analogs. Proceedings of the National Academy of Sciences. 1999; 96:1492-1497.

Other Relevent Publications:

9. Ruiz-Jarabo, C.M., Ly, C., Domingo, E., Torre, J.C. Lethal mutagenesis of the prototypic arenavirus lymphocytic chroriomeningitis virus (LCMV). Virology. 2003; 308(1):37-47.

10. Contreras, A.M., Hiasa, Y., He, W., Terella, A., Schmidt, E.V., Chung, R.T. Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system. Journal of Virology. 2002; 76(17):8505-8517.

11. Lanford, R.E., Chavez, D., Guerra, B., Lau, J.Y.N., Hong, Z., Brasky, K.M., Beames, B. Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes. Journal of Virology. 2001; 75(17):8074-8081.

12. Crotty, S., Cameron, C.E., Andino, R. RNA virus error catastrophe: direct molecular test by using ribavirin. Proceedings of the National Academy of Sciences USA. 2001; 98:6895-6900.

13. Sierra, S., Dávila, M., Lowenstein, P.R., Domingo, E. Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivity. Journal of Virology. 2000; 74(18):8316-8323.

Fundamental Papers:

14. Eigen, M. Viral quasispecies. Scientific American. 1993. July:42.

15. Gerrish, P.J., Garcia-Lerma, J.G. Mutation rate and the efficacy of antimicrobial drug treatment. Lancet Infectious Diseases. 2003; 3(1):28-32.